Sighicelli first studied piano then instrumental composition (notably with Gérard Grisey), electroacoustic and improvisation at the Paris Conservatory from which he graduated in 1998 with first prizes in these fields. He was in residency at the Villa Medicis in 2003-2004. In 2003, he was awarded the H.Dugardin prize from the SACEM. His works have been played and/or commissioned by organisms such as Ina-GRM and Radio France, the Court-circuit, Itinéraire, Ictus and 2e2m ensembles, the Ministry of Culture, Quatuor Arditti, Collegium Novum Zürich, Percussions de Strasbourg and the National Orchestra of Montpellier...
Along with Benjamin de la Fuente, he founded the company Sphota in 2000 and Caravaggio in 2004. With these two groups, he has given numerous concerts and performances in France and abroad (Festival Musica, Why Note, Tage fur neue musik, Traiettorie, Agora, Berliner Festpiel, San Sebastian, Roma Europa...).
A self-taught filmmaker, he has created several video works for stage productions, notably for his own shows (Marée noire, L’Île solaire). His instrumental works are published by Jobert (Lemoine). He released two albums of his music : Marée noire (label d’autres cordes), 12 Etudes for piano and sampler (label Cuicatl). His work is infused by the "sound continuum"